Description

3-(Pyridin-2-Ylmethoxy)Phenylboronic Acid is a specialized organoboron compound featuring a pyridine-linked phenylboronic acid scaffold, making it a valuable building block in modern synthetic chemistry. Its core value lies in its dual functionality, serving as a key intermediate for constructing complex molecules via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific aromatic frameworks.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized as a handle for bioconjugation and affinity chromatography due to boronic acid's affinity for diols.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel bidentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	3-(Pyridin-2-Ylmethoxy)Phenylboronic Acid
CAS No.	1256355-50-6
Molecular Formula	C12H12BNO3
Molecular Weight	229.04 g/mol
Synonyms	[2-(3-Boronophenoxy)methyl]pyridine; 3-[(Pyridin-2-yl)methoxy]benzeneboronic Acid; 2-[(3-Boronophenoxy)methyl]pyridine; 3-(2-Pyridylmethoxy)phenylboronic Acid; 3-Pyridin-2-ylmethoxyphenylboronic Acid; B-[3-[(Pyridin-2-yl)methoxy]phenyl]boronic Acid
EINECS	Contact for details

Quality Control

Our 3-(Pyridin-2-Ylmethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. Due to its hygroscopic and easily oxidized nature, the container must be sealed immediately after use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.