Description

2-Methoxypyridine-3-Boronic Acid Hydrate is a versatile organoboron building block, specifically a pyridine-substituted boronic acid derivative. This compound is essential for modern synthetic chemistry, enabling the efficient construction of complex molecules through reliable cross-coupling reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the methoxypyridine moiety can impart specific biological activity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes and sensors for studying biological processes due to its ability to form stable covalent bonds under mild conditions.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel bidentate or polydentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up production for clients.

Basic Information

Product Name	2-Methoxypyridine-3-Boronic Acid Hydrate
CAS No.	1256355-25-5
Molecular Formula	C6H8BNO3 • xH2O
Molecular Weight	152.95 (Anhydrous Basis)
Synonyms	(2-Methoxypyridin-3-yl)boronic acid hydrate; 3-Borono-2-methoxypyridine hydrate; 2-Methoxy-3-pyridineboronic acid hydrate; 2-Methoxypyridin-3-ylboronic acid; 3-(2-Methoxypyridinyl)boronic acid; 2-Methoxy-3-pyridinylboronic acid; 2-MeO-3-PyB(OH)2 hydrate
EINECS	Contact for details

Quality Control

Our 2-Methoxypyridine-3-Boronic Acid Hydrate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Anhydrous Basis)
Water Content (KF)	≤ 10.0% w/w
Assay (NMR)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.