Description

1-(1-Borono-1-Phenylmethyl)-1H-Pyrazole-4-Boronic Acid is a specialized bifunctional boronic acid derivative that serves as a versatile building block in advanced organic synthesis. Its molecular architecture, featuring two distinct boronic acid groups, makes it a critical precursor for constructing complex molecules through cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents. Its unique structure enables precise molecular assembly, facilitating the creation of targeted chemical libraries and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl bond formations.
• Material Science Research: Serves as a monomer or linker for constructing organic frameworks, polymers, and advanced functional materials with tailored properties.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and sensors that leverage boronic acid-diol interactions for detection and imaging applications.
• Catalyst Ligand Synthesis: Acts as a starting material for synthesizing sophisticated ligands used in homogeneous catalysis.
• Academic & Process R&D: Employed in research laboratories for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Item	Details
Product Name	1-(1-Borono-1-Phenylmethyl)-1H-Pyrazole-4-Boronic Acid
CAS No.	1256355-17-5
Molecular Formula	C11H12B2N2O4
Molecular Weight	245.85 g/mol
Synonyms	1-(Borono(phenyl)methyl)-1H-pyrazole-4-boronic acid; 1-(1-Borono-1-phenylethyl)-1H-pyrazole-4-boronic acid (common misnomer); 1-(α-Boronobenzyl)-1H-pyrazole-4-boronic acid; Bifunctional Pyrazole Boronic Acid; 1H-Pyrazole-4-boronic acid, 1-(boronophenylmethyl)-; 1-(Phenylboronomethyl)-1H-pyrazole-4-boronic acid; 4-Borono-1-(1-borono-1-phenylethyl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 1-(1-Borono-1-Phenylmethyl)-1H-Pyrazole-4-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality commitment ensures batch-to-batch consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will compromise purity and reactivity. Keep the original container sealed and allow it to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (NMR)	≥ 97%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.