Description

2-Butoxy-4-Chlorophenylboronic Acid is a specialized organoboron compound widely used as a key synthetic intermediate in cross-coupling reactions. Its value lies in enabling the efficient construction of complex biaryl structures, which are crucial scaffolds in advanced material and pharmaceutical research. This high-purity building block is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active compounds and functional polymers.

Application

• Pharmaceutical Intermediate: A critical building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides that require specific chlorinated biphenyl structures.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of novel bidentate or polydentate ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	2-Butoxy-4-Chlorophenylboronic Acid
CAS No.	1256355-07-3
Molecular Formula	C10H14BClO3
Molecular Weight	228.48 g/mol
Synonyms	(2-Butoxy-4-chlorophenyl)boronic acid; 4-Chloro-2-butoxyphenylboronic acid; 2-Butoxy-4-chlorobenzeneboronic acid; B-(2-Butoxy-4-chlorophenyl)boronic acid; 2-n-Butoxy-4-chlorophenylboronic Acid; (4-Chloro-2-butoxyphenyl)boronic Acid; Boronic acid, B-(2-butoxy-4-chlorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Butoxy-4-Chlorophenylboronic Acid is manufactured under strict quality management protocols. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity, NMR confirmation, and residual solvent profiles. Our quality systems ensure traceability and consistency, supporting cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.