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2,4-Dichloro-5-(2-Methoxyethoxy)Phenylboronic Acid CAS NO 1256354-89-8


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CAS No.:1256354-89-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,4-Dichloro-5-(2-Methoxyethoxy)Phenylboronic Acid is a high-purity, functionalized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, where the boronic acid group enables Suzuki-Miyaura cross-coupling reactions, and the substituted phenyl ring provides a versatile scaffold for further modification. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and advanced materials.

Application

  • Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
  • Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators with enhanced efficacy.
  • Material Science Research: Building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
  • Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
  • Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name 2,4-Dichloro-5-(2-Methoxyethoxy)Phenylboronic Acid
CAS No. 1256354-89-8
Molecular Formula C9H11BCl2O4
Molecular Weight 273.90 g/mol
Synonyms [2,4-Dichloro-5-(2-methoxyethoxy)phenyl]boronic acid; 2,4-Dichloro-5-(2-methoxyethoxy)benzeneboronic acid; 5-(2-Methoxyethoxy)-2,4-dichlorophenylboronic acid; (2,4-Dichloro-5-(2-methoxyethoxy)phenyl)boronic acid; Boronic acid, B-[2,4-dichloro-5-(2-methoxyethoxy)phenyl]-; CAS 1256354-89-8
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Quality Control

Our 2,4-Dichloro-5-(2-Methoxyethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support development from research to commercial scale with consistent quality and full traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Heavy Metals ≤ 20 ppm
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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