Description

2,4-Dichloro-5-(2-(Dimethylamino)Ethoxy)Phenylboronic Acid CAS NO 1256346-48-1 is a specialized boronic acid derivative featuring a dimethylaminoethoxy side chain, making it a valuable building block in modern synthetic chemistry. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in creating complex aromatic and heteroaromatic scaffolds for oncology, CNS, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the introduction of the dichloro-phenylboronic acid moiety is required.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Ligand and Catalyst Development: The structural features make it useful for developing new ligands for catalysis or as a component in metal-organic frameworks (MOFs).
• Chemical Biology & Probe Synthesis: Employed in the creation of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for use in client-directed synthetic projects requiring precise cross-coupling steps.

Basic Information

Product Name	2,4-Dichloro-5-(2-(Dimethylamino)Ethoxy)Phenylboronic Acid
CAS No.	1256346-48-1
Molecular Formula	C10H14BCl2NO3
Molecular Weight	278.94 g/mol
Synonyms	[2,4-Dichloro-5-[2-(dimethylamino)ethoxy]phenyl]boronic acid; 2,4-Dichloro-5-(2-(dimethylamino)ethoxy)benzeneboronic acid; 5-(2-(Dimethylamino)ethoxy)-2,4-dichlorophenylboronic acid; B-[2,4-Dichloro-5-[2-(dimethylamino)ethoxy]phenyl]boronic acid; 1256346-48-1; AKOS025311315; 2,4-Dichloro-5-(2-(N,N-dimethylamino)ethoxy)phenylboronic Acid
EINECS	Contact for details

Quality Control

Our production of 2,4-Dichloro-5-(2-(Dimethylamino)Ethoxy)Phenylboronic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.