Description

4-Chloro-3-Isobutoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific halogenated aromatic frameworks.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for palladium-catalyzed C-C bond formation with aryl halides.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and functional materials.
• Material Science Research: A building block for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Useful in the synthesis of molecular probes and tags for biochemical research and diagnostics.

Basic Information

Product Name	4-Chloro-3-Isobutoxyphenylboronic Acid
CAS No.	1256346-37-8
Molecular Formula	C10H14BClO3
Molecular Weight	228.48 g/mol
Synonyms	(4-Chloro-3-isobutoxyphenyl)boronic acid; 4-Chloro-3-(2-methylpropoxy)benzeneboronic acid; B-(4-Chloro-3-isobutoxyphenyl)boronic acid; 4-Chloro-3-isobutoxybenzeneboronic Acid; 1256346-37-8; AKOS026712293; FT-0773732
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Isobutoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.