Description

4-Chloro-3-Isopropoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl moieties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its boronic acid functionality for structural diversification.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs or conductive films.
• Ligand & Catalyst Development: Employed in the preparation of sophisticated ligands for transition metal catalysis and organocatalysis.
• Chemical Biology & Proteomics: Utilized as a tool compound or linker in the development of biochemical probes and affinity purification reagents.
• Academic & Industrial R&D: A fundamental reagent for method development and exploratory synthesis in organic chemistry laboratories worldwide.

Basic Information

Product Name	4-Chloro-3-Isopropoxyphenylboronic Acid
CAS No.	1256346-35-6
Molecular Formula	C9H12BClO3
Molecular Weight	214.45 g/mol
Synonyms	(4-Chloro-3-isopropoxyphenyl)boronic acid; 4-Chloro-3-(1-methylethoxy)benzeneboronic acid; Boronic acid, B-(4-chloro-3-isopropoxyphenyl)-; 4-Chloro-3-isopropoxybenzeneboronic acid; 3-Isopropoxy-4-chlorophenylboronic acid; CAS 1256346-35-6
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Isopropoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.