Description

4-(2-Oxo-2-(Propylamino)Ethyl)Phenylboronic Acid is a specialized boronic acid derivative featuring a ketone and a propylamino side chain, making it a valuable bifunctional building block. This compound matters for its role as a key intermediate in modern synthetic chemistry, particularly in cross-coupling reactions and the synthesis of complex pharmaceutical molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other protein-protein interactions.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, essential for constructing complex biaryl structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific boronic acid functionalities.
• Material Science: Employed in the creation of organic electronic materials, sensors, and metal-organic frameworks (MOFs) due to its ability to coordinate with metals and form stable complexes.
• Chemical Biology & Proteomics: Utilized as a molecular probe or linker in activity-based protein profiling and the development of covalent inhibitors.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and catalysis research within university and CRO laboratories.

Basic Information

Product Name	4-(2-Oxo-2-(Propylamino)Ethyl)Phenylboronic Acid
CAS No.	1256345-81-9
Molecular Formula	C₁₁H₁₆BNO₃
Molecular Weight	221.06 g/mol
Synonyms	4-[2-Oxo-2-(propylamino)ethyl]benzeneboronic acid; 2-(4-Boronophenyl)-N-propylacetamide; [4-(2-Oxo-2-propylaminoethyl)phenyl]boronic acid; 4-(2-Oxo-2-propylaminoethyl)phenylboronic acid; N-Propyl-2-(4-boronophenyl)acetamide; B-[4-(2-Oxo-2-propylaminoethyl)phenyl]boronic acid; 4-(2-Oxo-2-(n-propylamino)ethyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4-(2-Oxo-2-(Propylamino)Ethyl)Phenylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC, NMR, and IR spectroscopy, are validated to provide reliable data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.