Description

3-Isobutoxy-5-Methylphenylboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, which is essential for constructing complex molecular architectures. This high-purity intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures prevalent in pharmaceutical candidates.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic photovoltaics, where specific aryl groups are required.
• Agrochemical Synthesis: Utilized in creating advanced herbicide and fungicide molecules that require specific substituted phenyl groups.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Acts as a versatile linker component in the design of bifunctional molecules for targeted protein degradation.

Basic Information

Product Name	3-Isobutoxy-5-Methylphenylboronic Acid
CAS No.	1256345-77-3
Molecular Formula	C12H19BO3
Molecular Weight	222.09 g/mol
Synonyms	(3-(Isobutoxy)-5-methylphenyl)boronic acid; 5-Methyl-3-isobutoxybenzeneboronic acid; 3-Methyl-5-isobutoxybenzeneboronic acid; Boronic acid, B-[3-(2-methylpropoxy)-5-methylphenyl]-; 1256345-77-3; 3-Isobutoxy-5-methyl-benzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Isobutoxy-5-Methylphenylboronic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade meets specifications suitable for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.