Description

4-Cyano-2-Methoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), especially those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with targeted activity and improved environmental profiles.
• Material Science Research: Serves as a monomer or building block for developing organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the life sciences industry.

Basic Information

Product Name	4-Cyano-2-Methoxyphenylboronic Acid
CAS No.	1256345-67-1
Molecular Formula	C9H8BNO3
Molecular Weight	189.98 g/mol
Synonyms	(4-Cyano-2-methoxyphenyl)boronic acid; 2-Methoxy-4-cyanophenylboronic acid; 4-Cyano-2-methoxybenzeneboronic acid; Boronic acid, B-(4-cyano-2-methoxyphenyl)-; 1256345-67-1; 4-CN-2-MeO-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 4-Cyano-2-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in sensitive coupling reactions. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.