Description

2-(Propylthio)-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid is a high-value organoboron building block, specifically a pyridine-based boronic acid derivative, essential for modern cross-coupling reactions. Its core value lies in enabling the precise and efficient synthesis of complex heterocyclic compounds, which are critical scaffolds in advanced material and pharmaceutical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-couplings for synthesizing novel drug candidates, particularly those containing trifluoromethyl-substituted pyridine motifs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the bioactivity-enhancing properties of the trifluoromethyl and sulfur-containing groups.
• Material Science Research: Serves as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronic devices.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying biological processes and target engagement.
• Process Chemistry & Scale-Up: Suitable for optimization and scaling of synthetic routes from laboratory to pilot plant scale for commercial production.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical suppliers offering bespoke synthesis services to client specifications.

Basic Information

Product Name	2-(Propylthio)-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid
CAS No.	1256345-56-8
Molecular Formula	C9H11BF3NO2S
Molecular Weight	265.06 g/mol
Synonyms	2-(Propylthio)-5-(trifluoromethyl)pyridine-3-boronic acid; 3-Borono-2-(propylthio)-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-propylthiopyridine-3-boronic acid; [2-(Propylsulfanyl)-5-(trifluoromethyl)pyridin-3-yl]boronic acid; 2-Propylthio-5-trifluoromethyl-3-pyridineboronic acid; Boronic acid, B-[2-(propylthio)-5-(trifluoromethyl)-3-pyridinyl]-
EINECS	Contact for details

Quality Control

Every batch of 2-(Propylthio)-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.