Description

5-Isoquinolineboronic Acid, Hcl is a high-purity boronic acid derivative, a key building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those containing the isoquinoline scaffold for potential therapeutic applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides through the construction of complex aromatic systems.
• Material Science: Serves as a building block for creating organic electronic materials, ligands for catalysts, and specialty polymers.
• Chemical Synthesis: Enables the formation of carbon-carbon bonds in Suzuki-Miyaura cross-coupling reactions to create diverse compound libraries for screening.
• Academic & R&D: A valuable reagent for methodological development and exploration of new synthetic pathways in university and corporate research laboratories.

Basic Information

Product Name	5-Isoquinolineboronic Acid, Hcl
CAS No.	1256345-46-6
Molecular Formula	C9H8BNO2·HCl
Molecular Weight	209.44 g/mol
Synonyms	5-Isoquinolineboronic Acid Hydrochloride; (Isoquinolin-5-yl)boronic Acid Hydrochloride; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline Hydrochloride; 5-Boronoisoquinoline Hydrochloride; 5-Isoquinolylboronic Acid HCl; CAS 1256345-46-6; 5-Quinolineboronic Acid Hydrochloride (common misnomer)
EINECS	Contact for details

Quality Control

Our 5-Isoquinolineboronic Acid, Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture and oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.