Description

4-(Boc-Amino)-2-Fluorobenzeneboronic Acid Pinacol Ester, 96% is a high-purity, protected boronic ester derivative designed for advanced organic synthesis. This compound is a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds under mild conditions. It is primarily utilized by medicinal chemists and process development scientists in the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures in drug discovery.
• Pharmaceutical Intermediate Synthesis: Serves as a protected precursor for introducing fluorinated aniline moieties into target molecules.
• Agrochemical Research: Used in the development of novel herbicides and pesticides with enhanced properties.
• Material Science: A building block for creating organic electronic materials and liquid crystals.
• Peptide Mimetics & PROTACs: Facilitates the synthesis of complex molecules for targeted protein degradation and biological studies.
• Chemical Biology Probes: Enables the labeling and study of biological systems through bioorthogonal chemistry.

Basic Information

Product Name	4-(Boc-Amino)-2-Fluorobenzeneboronic Acid Pinacol Ester, 96%
CAS No.	1256256-45-7
Molecular Formula	C₁₇H₂₅BFNO₄
Molecular Weight	337.20 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]-2-fluorobenzeneboronic acid pinacol ester; 2-Fluoro-4-[(tert-butoxycarbonyl)amino]benzeneboronic acid pinacol ester; 4-(Boc-amino)-2-fluorophenylboronic acid pinacol ester; N-Boc-4-borono-3-fluoroaniline pinacol ester; 4-(tert-Butoxycarbonylamino)-2-fluorophenylboronic acid pinacol ester; BOC-4-Amino-2-fluorophenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(Boc-Amino)-2-Fluorobenzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency meet the specified 96% minimum purity. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.