Description

2-(2,3-Dichlorophenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane is a high-purity, protected boronic ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where precise and reliable building blocks are required for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing biaryl structures.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific chlorinated aromatic motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Synthesis & Catalysis: Serves as a versatile reagent in academic and industrial laboratories for palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand & Catalyst Development: Acts as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-(2,3-Dichlorophenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane
CAS No.	1255760-30-5
Molecular Formula	C12H15BCl2O2
Molecular Weight	273.96 g/mol
Synonyms	5,5-Dimethyl-2-(2,3-dichlorophenyl)-1,3,2-dioxaborinane; (2,3-Dichlorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 2-(2,3-Dichlorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 2,3-Dichlorophenylboronic acid, cyclic ester with neopentyl glycol; Neopentyl glycol (2,3-dichlorophenyl)boronate; 2,3-Dichlorophenylboronic acid neopentyl glycol ester; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 2-(2,3-Dichlorophenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.