Description

Carbonic Acid, 4-Nitrophenyl [4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl Ester is a specialized organic compound featuring both a carbonate ester and a boronic ester pinacol group. This unique bifunctional structure makes it a valuable advanced synthetic intermediate for constructing complex molecules in pharmaceutical and materials chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for Suzuki-Miyaura cross-coupling reactions.
• Proteolysis-Targeting Chimera (PROTAC) Development: Used in the construction of linker molecules and warhead components for targeted protein degradation therapeutics.
• Boron Neutron Capture Therapy (BNCT) Agent Research: Serves as a precursor for developing boron-containing compounds used in experimental cancer treatments.
• Polymer & Materials Science: Intermediate for synthesizing functional monomers and polymers with specific optical or electronic properties.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, or insecticides with enhanced efficacy.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors for biological research and diagnostics.
• Organic Light-Emitting Diode (OLED) Materials: Precursor for electron-transport or host materials in display and lighting technologies.

Basic Information

Product Name	Carbonic Acid, 4-Nitrophenyl [4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl Ester
CAS No.	1254765-89-3
Molecular Formula	C20H22BNO6
Molecular Weight	383.21 g/mol
Synonyms	4-Nitrophenyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl) carbonate; (4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl (4-nitrophenyl) carbonate; 4-Nitrophenyl Carbonate Boronate Ester; PNPC-Boronate; 4-Nitrophenyl Chloroformate Boronate Analog; Boronic Acid Pinacol Ester Carbonate Derivative; (4-(Pinacolatoboryl)benzyl) 4-nitrophenyl carbonate
EINECS	Contact for details

Quality Control

Our production of Carbonic Acid, 4-Nitrophenyl [4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronic ester and carbonate functional groups.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.