Description

2-Oxo-2,3-Dihydrobenzo[D]Oxazol-5-Ylboronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, facilitating the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex drug candidates, particularly in medicinal chemistry programs targeting heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials and functional polymers.
• Cross-Coupling Reactions: Specifically designed as a stable, reactive partner in palladium-catalyzed Suzuki-Miyaura couplings to introduce the benzo[d]oxazolone moiety.
• Ligand and Catalyst Development: Utilized in the synthesis of specialized ligands for catalysis and molecular recognition.
• Chemical Biology Probes: Acts as a handle for bioconjugation and the development of activity-based probes for target identification.

Basic Information

Product Name	2-Oxo-2,3-Dihydrobenzo[D]Oxazol-5-Ylboronic Acid Pinacol Ester
CAS No.	1254319-58-8
Molecular Formula	C15H18BNO4
Molecular Weight	287.12 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-benzoxazolinone; Benzo[d]oxazol-5-yl-2(3H)-one, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one; 2-Oxo-2,3-dihydrobenzo[d]oxazole-5-boronic acid pinacol ester; 5-(Pinacolatoboryl)-2-benzoxazolinone; 5-(Pinacolboron)benzoxazol-2-one; 2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamic Acid Lactone
EINECS	Contact for details

Quality Control

Our 2-Oxo-2,3-Dihydrobenzo[D]Oxazol-5-Ylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) and handle it in a controlled, low-humidity environment. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.