Description

1-Bromo-4-Hydroxy-5,6,7,8-Tetrahydro-Naphthalene-2-Carboxylic Acid Methyl Ester is a high-purity, functionalized tetralin derivative that serves as a critical advanced intermediate in complex organic syntheses. Its unique bromo-hydroxy substitution pattern on the aromatic ring makes it a versatile building block for constructing pharmacologically active molecules and specialty chemicals. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for the development of advanced organic materials, including liquid crystals and specialty polymers.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry, including cross-coupling and functional group transformation reactions.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance and flavor molecules.

Basic Information

Product Name	1-Bromo-4-Hydroxy-5,6,7,8-Tetrahydro-Naphthalene-2-Carboxylic Acid Methyl Ester
CAS No.	1253654-65-7
Molecular Formula	C₁₂H₁₃BrO₃
Molecular Weight	285.14 g/mol
Synonyms	Methyl 1-Bromo-4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate; 1-Bromo-4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid methyl ester; 2-Naphthalenecarboxylic acid, 1-bromo-4-hydroxy-5,6,7,8-tetrahydro-, methyl ester; Methyl 1-bromo-4-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate (tautomer); 1-Bromo-4-hydroxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Hydroxy-5,6,7,8-Tetrahydro-Naphthalene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.