Description

Boronic Acid, B-[2-Fluoro-5-(Phenylmethoxy)-3-Pyridinyl]- is a high-purity, functionalized pyridinyl boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing complex heterocyclic systems.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Building block for constructing organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Potential use in developing molecular probes and inhibitors for biological target identification.
• Academic & R&D Laboratories: Fundamental reagent for methodological development in cross-coupling chemistry and heterocycle functionalization.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale synthesis under GMP or non-GMP conditions.

Basic Information

Product Name	Boronic Acid, B-[2-Fluoro-5-(Phenylmethoxy)-3-Pyridinyl]-
CAS No.	1253575-68-6
Molecular Formula	C12H11B F N O3
Molecular Weight	247.04 g/mol
Synonyms	[2-Fluoro-5-(benzyloxy)pyridin-3-yl]boronic acid; (2-Fluoro-5-(phenylmethoxy)-3-pyridinyl)boronic acid; 3-Pyridineboronic acid, 2-fluoro-5-(phenylmethoxy)-; B-[2-Fluoro-5-(benzyloxy)-3-pyridyl]boronic acid; 2-Fluoro-5-benzyloxypyridine-3-boronic acid; 5-(Benzyloxy)-2-fluoropyridine-3-boronic acid; 3-Borono-2-fluoro-5-(phenylmethoxy)pyridine
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[2-Fluoro-5-(Phenylmethoxy)-3-Pyridinyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including GMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.