Description

Trifluoro[[(3-Methoxybenzoyl)Amino]Methyl]-Borate Potassium Salt is a specialized organoboron reagent featuring a trifluoroborate moiety. This compound is valued for its enhanced stability and solubility in organic solvents compared to traditional boronic acids, making it a crucial intermediate in advanced synthetic chemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific boron-containing scaffolds.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysis, and other functional polymers.
• Suzuki-Miyaura Cross-Coupling: An air- and moisture-stable reagent for palladium-catalyzed carbon-carbon bond formation, offering improved handling and shelf-life.
• Chemical Biology & Proteomics: Potential use in bioconjugation and as a probe for studying biological processes due to its unique chemical handle.
• Catalyst & Ligand Development: Employed in the design and synthesis of novel boron-based catalysts and supporting ligands for asymmetric synthesis.

Basic Information

Product Name	Trifluoro[[(3-Methoxybenzoyl)Amino]Methyl]-Borate Potassium Salt
CAS No.	1253046-42-2
Molecular Formula	C10H10BF3KNO3
Molecular Weight	295.09 g/mol
Synonyms	Potassium (3-Methoxybenzamido)methyltrifluoroborate; Potassium Trifluoro[(3-Methoxybenzoylamino)methyl]borate; N-[(Trifluoroboratomethyl)carbamoyl]-3-methoxybenzenaminium Potassium Salt; (3-Methoxybenzamidomethyl)trifluoroborate Potassium Salt; K-3-Methoxybenzamidomethyltrifluoroborate; Potassium [(3-Methoxybenzoyl)amino]methyltrifluoroboranuide; Trifluoro[(3-methoxybenzamido)methyl]borate Potassium Salt
EINECS	Contact for details

Quality Control

Our Trifluoro[[(3-Methoxybenzoyl)Amino]Methyl]-Borate Potassium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with custom purity grades, including research and GMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability. Recommended storage temperature is 2-8°C for optimal shelf life.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.