Description

Potassium Benzamidomethyltrifluoroborate (CAS NO 1253046-38-6) is a high-value organotrifluoroborate reagent, a crucial building block in modern synthetic chemistry. This compound is prized for its enhanced stability and reactivity profile compared to traditional boronic acids, enabling more efficient and robust cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the discovery and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored electronic or optical properties.
• Chemical Biology & Medicinal Chemistry: Serves as a stable handle for late-stage functionalization and bioconjugation strategies in probe and drug candidate development.
• Process Chemistry & Scale-up: Its improved stability makes it suitable for optimizing and scaling coupling reactions from lab to pilot plant scale.
• Academic & Industrial R&D: A fundamental tool for methodological development in new catalytic transformations and C-C bond-forming reactions.

Basic Information

Product Name	Potassium Benzamidomethyltrifluoroborate
CAS No.	1253046-38-6
Molecular Formula	C8H8BF3KNO
Molecular Weight	229.06 g/mol
Synonyms	Potassium (Benzamidomethyl)trifluoroborate; Benzamidomethyltrifluoroboronic Acid Potassium Salt; N-(Trifluoroboratomethyl)benzamide Potassium Salt; Potassium N-(Trifluoroboratomethyl)benzamide; Benzamide, N-(trifluoroboratomethyl)-, potassium salt (1:1); KBF3-CH2NHC(O)Ph
EINECS	Contact for details

Quality Control

Our Potassium Benzamidomethyltrifluoroborate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing including NMR (1H, 13C, 11B, 19F), HPLC purity analysis, and KF titration to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided to guarantee the material meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic (moisture-sensitive) nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
11B NMR Purity	≥ 95%
Water Content (KF)	≤ 2.0 %
Solubility	Soluble in common polar organic solvents (e.g., DMF, DMSO, MeOH)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.