Description

1H-Indole-5-Carboxylic Acid, 4-Fluoro-, Methyl Ester is a high-purity fluorinated indole derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and physical properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, neurology, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom and indole core can enhance bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLEDs and semiconductors, due to its conjugated indole structure.
• Chemical Biology & Proteomics: Employed as a fluorescent probe or a tagging reagent for studying biological processes and protein interactions.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	1H-Indole-5-Carboxylic Acid, 4-Fluoro-, Methyl Ester
CAS No.	1252782-43-6
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	4-Fluoro-1H-indole-5-carboxylic acid methyl ester; Methyl 4-fluoro-1H-indole-5-carboxylate; 4-Fluoroindole-5-carboxylic acid methyl ester; 5-(Methoxycarbonyl)-4-fluoro-1H-indole; 1H-Indole-5-carboxylic acid, 4-fluoro-, methyl ester; 1252782-43-6
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-5-Carboxylic Acid, 4-Fluoro-, Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP-compliant research and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.