Description

Indazole-4-Boronic Acid, HCl is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient formation of carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those containing the indazole heterocycle for oncology and CNS research.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a versatile boronic acid partner for palladium-catalyzed coupling with aryl/vinyl halides to construct biaryl and other conjugated systems.
• Agrochemical Synthesis: Employed in the research and development of advanced herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysts, and advanced polymers.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) agents due to its reactive boronic acid moiety.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Product Name	Indazole-4-Boronic Acid, HCl
CAS No.	1252598-02-9
Molecular Formula	C7H8BClN2O2
Molecular Weight	198.41 g/mol
Synonyms	1H-Indazole-4-boronic acid hydrochloride; 4-Indazoleboronic acid HCl salt; 4-(Boronyl)-1H-indazole hydrochloride; Indazol-4-ylboronic acid hydrochloride; 1H-Indazol-4-ylboronic acid hydrochloride; B-(1H-Indazol-4-yl)boronic acid hydrochloride; 1252598-02-9; Indazole-4-BA, HCl
EINECS	Contact for details

Quality Control

Every batch of Indazole-4-Boronic Acid, HCl is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are supplied with each shipment, detailing key parameters such as assay (HPLC), purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.