Description

4-Piperidinol, 1-[5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyridinyl]- is a high-value, multi-functional chemical building block that combines a piperidine scaffold with a pyridine-boronic ester moiety. This structure makes it a critical intermediate for modern synthetic chemistry, particularly in the development of complex pharmaceutical candidates and advanced materials. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Suzuki-Miyaura Cross-Coupling Reactions: The boronic ester functional group makes it an essential reagent for forming carbon-carbon bonds, a fundamental step in constructing complex organic molecules.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening libraries and for structure-activity relationship (SAR) studies to optimize lead compounds.
• Ligand Synthesis: Serves as a precursor for creating novel ligands used in catalysis and material science.
• Agrochemical Research: Intermediate in the development of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.

Basic Information

Product Name	4-Piperidinol, 1-[5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyridinyl]-
CAS No.	1251948-86-3
Molecular Formula	C16H25BN2O3
Molecular Weight	304.19 g/mol
Synonyms	1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperidin-4-ol; 4-Hydroxy-1-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridyl]piperidine; 1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)-4-piperidinol; 4-Piperidinol, 1-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl)-; 2-(6-(4-Hydroxypiperidin-1-yl)pyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-Piperidinol derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and moisture uptake. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.