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5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furo[2,3-B]Pyridine CAS NO 1251728-92-3


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CAS No.:1251728-92-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furo[2,3-B]Pyridine is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting various therapeutic areas.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its ability to introduce the furopyridine moiety.
  • Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
  • Chemical Biology & Probe Development: Employed in the creation of molecular probes and labeled compounds for biochemical and diagnostic applications.
  • Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furo[2,3-B]Pyridine
CAS No. 1251728-92-3
Molecular Formula C15H18BNO3
Molecular Weight 271.12 g/mol
Synonyms 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)furo[2,3-b]pyridine; Furo[2,3-b]pyridine-5-boronic acid pinacol ester; 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)furo[2,3-b]pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-furo[2,3-b]pyridine; 5-Boronic acid pinacol ester furo[2,3-b]pyridine; CAS 1251728-92-3
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Quality Control

Our production of 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furo[2,3-B]Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. For long-term storage, consider storing under an inert gas blanket in a desiccator.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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