Description

2-Bromo-4-Fluoro-1-(Methoxymethyl)Benzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring bromine and fluorine substituents alongside a methoxymethyl group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the reactivity of its halogen atoms.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced functional molecules used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in both academic and industrial laboratories.

Basic Information

Product Name	2-Bromo-4-Fluoro-1-(Methoxymethyl)Benzene
CAS No.	1251222-82-8
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	1-Bromo-2-fluoro-5-(methoxymethyl)benzene; 2-Bromo-4-fluoro-1-(methoxymethyl)benzene; Benzene, 2-bromo-4-fluoro-1-(methoxymethyl)-; 2-Bromo-4-fluoro-α-methoxytoluene; α-Methoxy-2-bromo-4-fluorotoluene; 2-Bromo-4-fluorobenzyl methyl ether; (2-Bromo-4-fluorophenyl)methanol methyl ether
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-1-(Methoxymethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.