Description

1-(3-Chlorophenyl)But-3-En-1-Amine is a versatile chiral amine intermediate featuring a chlorophenyl group and a terminal alkene functionality. This compound is of significant value in organic synthesis, particularly for the construction of complex molecules in pharmaceutical and agrochemical research. It serves as a critical building block for medicinal chemists and process development scientists seeking to introduce specific stereochemistry and aromatic chlorination patterns into target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the chlorophenyl moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a chiral backbone for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: The amine and alkene groups allow for its incorporation as a monomer or cross-linking agent in specialty polymers and resins.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and process chemistry optimization in R&D laboratories.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fine chemicals and dyes.

Basic Information

Item	Detail
Product Name	1-(3-Chlorophenyl)But-3-En-1-Amine
CAS No.	1250174-71-0
Molecular Formula	C10H12ClN
Molecular Weight	181.66 g/mol
Synonyms	1-(3-Chlorophenyl)-3-buten-1-amine; 3-Chloro-α-vinylbenzylamine; (3-Chlorophenyl)but-3-en-1-amine; 1-Amino-1-(3-chlorophenyl)-3-butene; 3-Chloro-α-vinylbenzenemethanamine; But-3-en-1-amine, 1-(3-chlorophenyl)-; 1-(3-Chlorophenyl)-3-butenylamine
EINECS	Contact for details

Quality Control

Our 1-(3-Chlorophenyl)But-3-En-1-Amine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.