Description

2-Chloro-4-[(Cyclopropylcarbonyl)Amino]Benzoic Acid CAS NO 1249352-65-5 is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzoic acid derivative structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and R&D laboratories focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial building block in multi-step synthetic routes for target API molecules.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Institutional Research: Employed in university and research institute laboratories for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Item	Detail
Product Name	2-Chloro-4-[(Cyclopropylcarbonyl)Amino]Benzoic Acid
CAS No.	1249352-65-5
Molecular Formula	C11H10ClNO3
Molecular Weight	239.66 g/mol
Synonyms	2-Chloro-4-(cyclopropanecarboxamido)benzoic acid; 4-[(Cyclopropylcarbonyl)amino]-2-chlorobenzoic acid; Benzoic acid, 2-chloro-4-[(cyclopropylcarbonyl)amino]-; 1249352-65-5; 2-Chloro-4-(cyclopropylcarbamoyl)benzoic acid (tautomeric form); CPCA; 2-Chloro-4-cyclopropanecarboxamidobenzoic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-[(Cyclopropylcarbonyl)Amino]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.