Description

1-(3-Fluorophenyl)-1H-Imidazole-4-Carboxylic Acid is a high-purity fluorinated imidazole derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile scaffold for introducing both the imidazole heterocycle and a fluorine-substituted aromatic ring into target molecules, enabling the fine-tuning of physicochemical and biological properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients, particularly in medicinal chemistry programs targeting enzyme inhibition.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in kinase inhibitor and antifungal discovery programs.
• Agrochemical Research: Used in the synthesis of experimental fungicides and herbicides, where the fluorine atom enhances bioavailability and metabolic stability.
• Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential building block for advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or functional polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	1-(3-Fluorophenyl)-1H-Imidazole-4-Carboxylic Acid
CAS No.	1249035-17-3
Molecular Formula	C10H7FN2O2
Molecular Weight	206.18 g/mol
Synonyms	1-(3-Fluorophenyl)-1H-imidazole-4-carboxylic acid; 4-Imidazolecarboxylic acid, 1-(3-fluorophenyl)-; 1-(3-Fluorophenyl)imidazole-4-carboxylic acid; 3-Fluorophenylimidazole-4-carboxylic acid; 1H-Imidazole-4-carboxylic acid, 1-(3-fluorophenyl)-; 1249035-17-3; 1-(m-Fluorophenyl)-1H-imidazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)-1H-Imidazole-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.