Description

3-Bromo-4-Methylpicolinaldehyde is a versatile and high-value brominated heterocyclic aldehyde building block. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research, where its unique structure enables the introduction of key functional groups. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated picoline scaffold.
• Ligand Synthesis: Serves as a crucial starting material for creating complex chelating ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: Utilized in the development of organic electronic materials and functional polymers.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Bromo-4-Methylpicolinaldehyde
CAS No.	1248738-15-9
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	3-Bromo-4-methylpyridine-2-carboxaldehyde; 2-Pyridinecarboxaldehyde, 3-bromo-4-methyl-; 4-Methyl-3-bromopicolinaldehyde; 3-Bromo-4-methyl-2-pyridinecarboxaldehyde; 3-Bromo-4-methylpicolinaldehyde; 3-Bromo-4-methyl-2-formylpyridine; 3-Br-4-Me-Picolinaldehyde
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Methylpicolinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.