Description

1-[4-(Trifluoromethyl)Phenyl]Butan-2-One CAS NO 1248106-81-1 is a high-purity fluorinated aromatic ketone, a key building block valued for its trifluoromethyl group which imparts unique electronic and steric properties to target molecules. This compound is essential for researchers and manufacturers requiring precise chemical intermediates to develop advanced materials and active pharmaceutical ingredients (APIs). It is primarily targeted at the pharmaceutical, agrochemical, and specialty chemical industries for applications in synthesis and R&D.

Application

• Pharmaceutical Intermediate: A crucial synthon in the research and development of novel drug candidates, particularly for introducing the metabolically stable trifluoromethyl group.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the CF3 moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a key starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Organic Synthesis Building Block: Employed in various organic reactions, including cross-coupling and condensation reactions, to construct complex molecular architectures.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic methodologies and material properties.
• Specialty Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymer chains, altering their solubility, thermal stability, and surface properties.

Basic Information

Product Name	1-[4-(Trifluoromethyl)Phenyl]Butan-2-One
CAS No.	1248106-81-1
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	4'-(Trifluoromethyl)butyrophenone; 1-[4-(Trifluoromethyl)phenyl]butan-2-one; 2-Butanone, 1-[4-(trifluoromethyl)phenyl]-; p-Trifluoromethylbutyrophenone; α-Methyl-β-oxo-4-(trifluoromethyl)benzenepropane; 4-Trifluoromethylbutyrophenone; 4'-Trifluoromethylbutyrophenone; 1-(4-Trifluoromethylphenyl)butan-2-one
EINECS	Contact for details

Quality Control

Our 1-[4-(Trifluoromethyl)Phenyl]Butan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the high standards required for pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.