Description

3-Methyl-1-[4-(Trifluoromethyl)Phenyl]Butan-2-One is a specialized organic compound featuring a phenyl ketone core substituted with a trifluoromethyl group. This structure is significant as it combines ketone reactivity with the unique electronic and lipophilic properties imparted by the fluorine atoms, making it a valuable advanced pharmaceutical intermediate and a versatile building block in synthetic chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders or requiring enhanced metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty monomers or ligands used in the development of advanced polymers and catalysts.
• Organic Synthesis: Acts as a versatile electrophile or a functionalized aromatic component in multi-step synthetic routes for complex organic molecules.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on understanding the effects of fluorinated aromatic systems on chemical reactivity and physical properties.

Basic Information

Item	Details
Product Name	3-Methyl-1-[4-(Trifluoromethyl)Phenyl]Butan-2-One
CAS No.	1247829-73-7
Molecular Formula	C12H13F3O
Molecular Weight	230.23 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-3-methylbutan-2-one; 3-Methyl-1-[4-(trifluoromethyl)phenyl]-2-butanone; 4'-Trifluoromethyl-3-methylbutyrophenone; α-Isopropyl-4'-(trifluoromethyl)acetophenone; 2-Butanone, 3-methyl-1-[4-(trifluoromethyl)phenyl]-; 4-(Trifluoromethyl)phenyl isopropyl ketone (related)
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-1-[4-(Trifluoromethyl)Phenyl]Butan-2-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkali and fluoride sources; ensure appropriate segregation in storage areas. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.