Description

cis-2,6-Dimethyl-4-({4-[(E)-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethenyl]Phenyl}Methyl)Morpholine is a sophisticated boronic ester derivative that serves as a critical synthetic intermediate in modern organic chemistry. Its value lies in its dual functionality, combining a morpholine scaffold with a protected boronic acid group, enabling precise cross-coupling reactions and structural diversification. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for targeted therapies and small molecule inhibitors.
• Suzuki-Miyaura Cross-Coupling Reactions: The tetramethyl-1,3,2-dioxaborolane (pinacol boronic ester) group enables efficient palladium-catalyzed coupling with aryl halides, a cornerstone of C-C bond formation.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science & OLED Development: Serves as a precursor for creating advanced organic electronic materials and emissive layers in display technologies.
• Chemical Biology & Probe Synthesis: Utilized for labeling and modifying biomolecules or creating activity-based probes for biological target identification.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	cis-2,6-Dimethyl-4-({4-[(E)-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethenyl]Phenyl}Methyl)Morpholine
CAS No.	1247001-44-0
Molecular Formula	C21H32BNO3
Molecular Weight	357.30 g/mol
Synonyms	4-[(E)-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)ethenyl]benzyl-cis-2,6-dimethylmorpholine; (E)-2-(4-((cis-2,6-Dimethylmorpholino)methyl)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; cis-2,6-Dimethyl-4-[(E)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl]benzylmorpholine; Boronic acid, B-[2-[4-[(cis-2,6-dimethyl-4-morpholinyl)methyl]phenyl]ethenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; Pinacol (E)-2-(4-((2,6-cis-dimethylmorpholino)methyl)styryl)boronate
EINECS	Contact for details

Quality Control

Our production of cis-2,6-Dimethyl-4-({4-[(E)-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethenyl]Phenyl}Methyl)Morpholine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.