Description

(3-Oxo-3,4-Dihydro-2H-Benzo[B]-[1,4]Oxazin-6-Yl)Boronic Acid CAS NO 1246765-28-5 is a high-purity, advanced pharmaceutical intermediate belonging to the class of heterocyclic boronic acids. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules through efficient cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds for drug discovery and development programs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, essential for constructing drug-like molecules.
• Medicinal Chemistry Research: Used in the design and synthesis of libraries of compounds for high-throughput screening against biological targets.
• API Synthesis: Employed in the scalable production of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical studies.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and enzyme functions.
• Agrochemical Research: Potential application as an intermediate in the development of new agrochemicals and plant protection agents.

Basic Information

Product Name	(3-Oxo-3,4-Dihydro-2H-Benzo[B]-[1,4]Oxazin-6-Yl)Boronic Acid
CAS No.	1246765-28-5
Molecular Formula	C9H8BNO4
Molecular Weight	205.98 g/mol
Synonyms	6-Borono-3,4-dihydro-2H-1,4-benzoxazin-3-one; (3-Oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)boronic acid; 2H-1,4-Benzoxazin-3(4H)-one, 6-borono-; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1,4-benzoxazin-3(4H)-one (Pinacol ester precursor); Benzo[B][1,4]Oxazin-6-Ylboronic Acid Derivative
EINECS	Contact for details

Quality Control

Our (3-Oxo-3,4-Dihydro-2H-Benzo[B]-[1,4]Oxazin-6-Yl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.