Description

B-1H-Pyrrolo[2,3-B]Pyridin-4-Ylboronic Acid CAS NO 1246761-84-1 is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical industry, particularly for synthesizing novel heterocyclic compounds with potential therapeutic activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing the privileged pyrrolopyridine scaffold.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for constructing complex biaryl and heterobiaryl structures under mild reaction conditions.
• Medicinal Chemistry & Drug Discovery: Used extensively in lead optimization and library synthesis for creating novel molecules targeting various disease pathways.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science: Potential building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations that require reliable, high-quality building blocks for client projects.

Basic Information

Product Name	B-1H-Pyrrolo[2,3-B]Pyridin-4-Ylboronic Acid
CAS No.	1246761-84-1
Molecular Formula	C7H7BN2O2
Molecular Weight	161.96 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridin-4-ylboronic acid; 4-Borono-1H-pyrrolo[2,3-b]pyridine; 4-(1H-Pyrrolo[2,3-b]pyridin-4-yl)boronic acid; B-(1H-Pyrrolo[2,3-b]pyridin-4-yl)boronic Acid; 1246761-84-1; Pyrrolo[2,3-b]pyridine-4-boronic acid
EINECS	Contact for details

Quality Control

Our B-1H-Pyrrolo[2,3-B]Pyridin-4-Ylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and potentially air/moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.