Description

2-(2-Fluoro-6-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient, selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for complex molecule synthesis. CAS No. 1246632-96-1.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used to construct complex, fluorinated heterocycles found in modern herbicides, fungicides, and insecticides, enhancing their biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs, OFETs, and conductive polymers.
• Ligand & Catalyst Development: Employed in the preparation of novel boron-containing ligands and catalysts for asymmetric synthesis and polymerization processes.
• Chemical Biology & Probe Synthesis: Utilized to create fluorinated molecular probes and tags for imaging, diagnostics, and studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs producing bespoke organic compounds for client R&D and scale-up projects.

Basic Information

Product Name	2-(2-Fluoro-6-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1246632-96-1
Molecular Formula	C13H18BFO2
Molecular Weight	236.09 g/mol
Synonyms	2-Fluoro-6-methylbenzeneboronic acid pinacol ester; (2-Fluoro-6-methylphenyl)boronic acid pinacol ester; 2-(2-Fluoro-6-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2-fluoro-6-methylphenyl)boronate; 2-Fluoro-6-methylphenylboronic acid pinacol ester; 2-Fluoro-6-methylbenzeneboronic acid, pinacol ester; B-(2-Fluoro-6-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-6-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and lot-to-lot consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.