Description

tert-Butyl 4-(2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy)Piperidine-1-Carboxylate is a high-purity (96%) pharmaceutical intermediate featuring a key boronic ester functional group. This compound matters as a critical building block in modern organic synthesis, enabling efficient cross-coupling reactions for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal reagent for forming carbon-carbon bonds between aromatic rings, essential in medicinal chemistry.
• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those containing a piperidine scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the creation of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Acts as a building block for creating molecular tools used to study biological processes.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Item	Details
Product Name	tert-Butyl 4-(2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy)Piperidine-1-Carboxylate
CAS No.	1246372-53-1
Molecular Formula	C23H36BNO6
Molecular Weight	433.35 g/mol
Synonyms	1-Boc-4-(2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)piperidine; tert-Butyl 4-[2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]piperidine-1-carboxylate; 1,1-Dimethylethyl 4-[2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]-1-piperidinecarboxylate; 4-(2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)piperidine-1-carboxylic acid tert-butyl ester; BOC-Piperidine Boronic Ester Intermediate; Pinacol boronate ester of BOC-protected aminophenol.
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.