Description

(3-Chlorophenyl)Methyl-Trifluoroboranuide is a versatile organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its stability and reactivity as a coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heteroaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl moieties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where specific chlorophenyl groups are required for bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, liquid crystals, and polymers with tailored properties.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a stable, air- and moisture-tolerant boronic acid equivalent in palladium-catalyzed cross-coupling reactions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for the synthesis of labeled compounds and molecular probes for biochemical and diagnostic research.

Basic Information

Product Name	(3-Chlorophenyl)Methyl-Trifluoroboranuide
CAS No.	1246073-61-9
Molecular Formula	C7H6BClF3K
Molecular Weight	229.48 g/mol
Synonyms	Potassium (3-Chlorobenzyl)trifluoroborate; (3-Chlorobenzyl)trifluoroboronic Acid Potassium Salt; (3-Chlorophenyl)methyltrifluoroborate Potassium Salt; 3-Chlorobenzyltrifluoroboronate Potassium; 1-Chloro-3-(trifluoroboratomethyl)benzene Potassium Salt; K-3-Chlorobenzyltrifluoroborate; (m-Chlorobenzyl)trifluoroborate Potassium
EINECS	Contact for details

Quality Control

Our (3-Chlorophenyl)Methyl-Trifluoroboranuide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC for purity, and KF titration for moisture content, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹H NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Potassium Content	16.5 - 18.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.