Description

Potassium 4-Fluorobenzyltrifluoroborate is a high-purity organotrifluoroborate salt, a versatile and stable building block for advanced organic synthesis. Its primary value lies in its exceptional utility in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require reliable, moisture-stable intermediates for creating novel compounds.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing fluorinated biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the 4-fluorobenzyl moiety imparts specific biological activity.
• Materials Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers through palladium-catalyzed cross-coupling.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air- and moisture-tolerant boronic acid equivalent for coupling with various aryl/heteroaryl halides or triflates.
• Chemical Library Development: A valuable reagent for medicinal chemistry and high-throughput screening libraries to explore structure-activity relationships (SAR).
• Ligand and Catalyst Preparation: Used in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Item	Detail
Product Name	Potassium 4-Fluorobenzyltrifluoroborate
CAS No.	1246073-48-2
Molecular Formula	C8H6BF4K
Molecular Weight	219.04 g/mol
Synonyms	Potassium (4-Fluorobenzyl)trifluoroborate; 4-Fluorobenzyltrifluoroboronic Acid Potassium Salt; Potassium 4-Fluorobenzyl-Trifluoroborane; (4-Fluorophenyl)methyltrifluoroboronic Acid Potassium Salt; Potassium [(4-Fluorophenyl)methyl]trifluoroboranuide; K-4-Fluorobenzyltrifluoroborate; p-Fluorobenzyltrifluoroborate Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium 4-Fluorobenzyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and elemental analysis (EA), to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) in a dry environment to prevent decomposition. Keep away from strong acids and strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
¹H NMR Assay	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.