Description

5-(Trifluoromethyl)Thiazole-2-Carboxylic Acid is a high-value trifluoromethylated heterocyclic building block essential for modern synthetic chemistry. This compound matters for its role as a key precursor in the development of advanced pharmaceuticals and agrochemicals, where the trifluoromethyl group imparts desirable properties like metabolic stability and enhanced lipophilicity. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the thiazole and trifluoromethyl motifs contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold or labeling reagent in the design of enzyme inhibitors, probes, and molecular tools.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-(Trifluoromethyl)Thiazole-2-Carboxylic Acid
CAS No.	1246006-74-5
Molecular Formula	C5H2F3NO2S
Molecular Weight	197.13 g/mol
Synonyms	2-Thiazolecarboxylic acid, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-2-thiazolecarboxylic acid; 5-Trifluoromethylthiazole-2-carboxylic acid; 5-(Trifluoromethyl)-1,3-thiazole-2-carboxylic acid; 1246006-74-5; 5-Trifluoromethyl-2-thiazolecarboxylic acid; 5-(Trifluoromethyl)thiazole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Thiazole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.