Description

5-Methyl-1H-Indazol-4-Yl-4-Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for constructing indazole-containing drug candidates in medicinal chemistry research and API synthesis.
• Suzuki-Miyaura Cross-Coupling: Serves as a pivotal boronic acid reagent for palladium-catalyzed carbon-carbon bond formation to create complex molecular architectures.
• Agrochemical Research: Used in the discovery and synthesis of novel herbicides, fungicides, and insecticides with indazole cores.
• Material Science: Potential building block for creating organic electronic materials and advanced polymers via cross-coupling methodologies.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for biological target investigation.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical producers offering bespoke synthesis services.

Basic Information

Item	Details
Product Name	5-Methyl-1H-Indazol-4-Yl-4-Boronic Acid
CAS No.	1245816-10-7
Molecular Formula	C8H9BN2O2
Molecular Weight	176.00 g/mol
Synonyms	5-Methyl-1H-indazol-4-ylboronic acid; (5-Methyl-1H-indazol-4-yl)boronic acid; 4-Borono-5-methyl-1H-indazole; 5-Methyl-4-indazoleboronic acid; 5-Methyl-1H-indazole-4-boronic acid; 1245816-10-7; 5-Methylindazole-4-boronic Acid
EINECS	Contact for details

Quality Control

Our 5-Methyl-1H-Indazol-4-Yl-4-Boronic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.