Description

7-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-1-Oxo-, Methyl Ester is a high-purity, synthetic organic compound belonging to the tetrahydroisoquinoline class, serving as a critical building block in advanced chemical synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. This intermediate is essential for medicinal chemists and process development scientists working in drug discovery, agrochemical innovation, and the synthesis of fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting neurological disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and specialty performance chemicals.
• Academic & R&D: Utilized in university and institutional laboratories for methodological development and novel reaction pathway exploration.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for scale-up and custom synthesis projects.

Basic Information

Product Name	7-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-1-Oxo-, Methyl Ester
CAS No.	1245798-40-6
Molecular Formula	C12H13NO3
Molecular Weight	219.24 g/mol
Synonyms	1-Oxo-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid methyl ester; Methyl 1-oxo-1,2,3,4-tetrahydroisoquinoline-7-carboxylate; Methyl 1,2,3,4-tetrahydro-1-oxo-7-isoquinolinecarboxylate; 7-(Methoxycarbonyl)-1,2,3,4-tetrahydroisoquinolin-1-one; 1,2,3,4-Tetrahydro-1-oxo-7-isoquinolinecarboxylic Acid Methyl Ester; 1245798-40-6
EINECS	Contact for details

Quality Control

Our production of 7-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-1-Oxo-, Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for research and commercial synthesis. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We operate under a quality system designed to meet the exacting standards of our global pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.