Description

1-Bromo-3,5-Bis(tert-Butoxymethyl)Benzene is a high-value, multi-functional aromatic building block designed for advanced organic synthesis. This compound matters because its unique structure, featuring both a bromine substituent and two tert-butoxymethyl protecting groups, offers exceptional versatility for constructing complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as ligand synthesis, polymer modification, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly where sterically hindered aromatic systems are required.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging its reactivity for creating diverse bioactive compounds.
• Ligand and Catalyst Development: Serves as a sophisticated building block for constructing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Advanced Material Precursor: Employed in the synthesis of monomers and functional units for high-performance polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl and other extended aromatic systems.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	1-Bromo-3,5-Bis(tert-Butoxymethyl)Benzene
CAS No.	1245644-77-2
Molecular Formula	C₁₇H₂₇BrO₂
Molecular Weight	343.30 g/mol
Synonyms	3,5-Bis[(2-methyl-2-propanyl)oxy]methyl-1-bromobenzene; 1-Bromo-3,5-bis[(tert-butoxy)methyl]benzene; Benzene, 1-bromo-3,5-bis[(2-methyl-2-propanyl)oxy]methyl-; 3,5-Bis(tert-butoxymethyl)bromobenzene; α,α'-Di-tert-butoxy-m-bromotoluene; 1-Bromo-3,5-di(tert-butoxymethyl)benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3,5-Bis(tert-Butoxymethyl)Benzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.