Description

Ethyl 3-(Trifluoromethyl)-1,2,4-oxadiazole-5-carboxylate is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique trifluoromethylated oxadiazole core, which imparts desirable properties like metabolic stability and enhanced lipophilicity to target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients. The CAS number for this product is 1245643-72-4.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating the metabolically stable trifluoromethyl-oxadiazole pharmacophore.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the fluorinated heterocycle can improve biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers and advanced materials that require fluorinated components for specific thermal or chemical resistance properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems due to the distinct properties of the fluorine atoms.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Ethyl 3-(Trifluoromethyl)-1,2,4-oxadiazole-5-carboxylate
CAS No.	1245643-72-4
Molecular Formula	C6H5F3N2O3
Molecular Weight	210.11 g/mol
Synonyms	Ethyl 3-(trifluoromethyl)-1,2,4-oxadiazole-5-carboxylate; 5-Ethoxycarbonyl-3-trifluoromethyl-1,2,4-oxadiazole; 1,2,4-Oxadiazole-5-carboxylic acid, 3-(trifluoromethyl)-, ethyl ester; Ethyl 3-(trifluoromethyl)-1,2,4-oxadiazole-5-carboxylate; Ethyl 5-(trifluoromethyl)-1,2,4-oxadiazole-3-carboxylate (isomer); TFMO-Carboxylate Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Trifluoromethyl)-1,2,4-oxadiazole-5-carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemical production, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be stored away from direct light exposure. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.