Description

2-Fluoro-4-Hydroxy-n-Methylbenzamide is a specialized fluorinated benzamide derivative, a key building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorine substitution and amide functionality enable precise molecular design. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine atom can improve lipophilicity and target binding.
• Ligand & Catalyst Development: Serves as a precursor or functional component in the design of specialized ligands for catalysis and molecular recognition applications.
• Material Science Precursor: Employed in the synthesis of advanced polymers or liquid crystals where fluorinated aromatic units impart specific thermal and chemical resistance properties.
• Chemical Biology Probe Synthesis: Utilized to create fluorescent tags or molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	2-Fluoro-4-Hydroxy-n-Methylbenzamide
CAS No.	1243392-80-4
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	2-Fluoro-4-hydroxy-N-methylbenzamide; 4-Hydroxy-2-fluoro-N-methylbenzamide; N-Methyl-2-fluoro-4-hydroxybenzamide; 2-Fluoro-4-hydroxy-N-methyl-benzamide; Benzamide, 2-fluoro-4-hydroxy-N-methyl-; 1243392-80-4
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Hydroxy-n-Methylbenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete batch-specific data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.