Description

3-Methoxy-4-Pyridineboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides that require specific pyridine-based architectures.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Facilitates the creation of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Process Chemistry & Scale-up: Suitable for route development and optimization from milligram to kilogram scale in API manufacturing.
• Academic & Contract Research: A valuable tool for methodology development and exploring new chemical space in university and CRO laboratories.

Basic Information

Product Name	3-Methoxy-4-Pyridineboronic Acid Pinacol Ester
CAS No.	1243312-43-7
Molecular Formula	C₁₂H₁₈BNO₃
Molecular Weight	235.09 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methoxypyridine; 3-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Methoxypyridine-4-boronic acid pinacol ester; 3-Methoxy-4-pyridinylboronic acid pinacol ester; 4-Pyridineboronic acid, 3-methoxy-, 1,1-dimethylethyl ester; Boronic acid, B-[3-methoxy-4-pyridinyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 3-Methoxy-4-Pyridineboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, assay, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	95.0% - 105.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.