Description

4-Bromo-trans-β-Styrylboronic Acid Pinacol Ester is a high-purity, advanced boronic ester building block crucial for modern synthetic chemistry. This compound matters as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex organic molecules and advanced materials. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of complex biaryl and styryl derivatives.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly in creating molecular scaffolds for oncology and CNS-targeted therapies.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients in crop protection and herbicide formulations.
• Materials Science & OLED Development: Employed in the synthesis of organic semiconductors, light-emitting materials, and advanced polymers for electronic applications.
• Ligand and Catalyst Preparation: Useful for constructing sophisticated ligand frameworks in transition metal catalysis.
• Chemical Biology & Probe Development: Facilitates the synthesis of tagged molecules and probes for studying biological pathways and protein interactions.

Basic Information

Product Name	4-Bromo-trans-β-Styrylboronic Acid Pinacol Ester
CAS No.	1242770-51-9
Molecular Formula	C14H18BBrO2
Molecular Weight	309.01 g/mol
Synonyms	4-Bromostyrylboronic Acid Pinacol Ester; (E)-4-Bromostyrylboronic Acid Pinacol Ester; trans-4-Bromostyrylboronic Acid Pinacol Ester; 4-Bromo-β-styrylboronic Acid Pinacol Ester; (E)-2-(4-Bromostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromo-trans-styrylboronic Acid Pinacol Ester; Pinacol (E)-4-Bromostyrylboronate; 4-BromostyrylBPin
EINECS	Contact for details

Quality Control

Our 4-Bromo-trans-β-Styrylboronic Acid Pinacol Ester is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and GC analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.