Description

4-Trifluoromethyl-trans-β-Styrylboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. Its value lies in its role as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, a cornerstone method for forming carbon-carbon bonds. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing drug candidates containing the trifluoromethyl group, which enhances metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a monomer or precursor for creating advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura couplings to introduce the styryl moiety into complex molecular architectures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating compound libraries for screening.
• Fluorine Chemistry: Exploited in the synthesis of fluorinated organic compounds, leveraging the unique properties of the CF3 group.

Basic Information

Product Name	4-Trifluoromethyl-trans-β-Styrylboronic Acid Pinacol Ester
CAS No.	1242770-50-8
Molecular Formula	C15H18BF3O2
Molecular Weight	298.11 g/mol
Synonyms	4-(Trifluoromethyl)styrylboronic acid pinacol ester; (E)-4-(Trifluoromethyl)styrylboronic acid pinacol ester; trans-4-Trifluoromethylstyrylboronic Acid Pinacol Ester; 2-(4-Trifluoromethylstyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-2-(4-(Trifluoromethyl)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-[2-[4-(trifluoromethyl)phenyl]ethenyl]-, 1,1-dimethylethyl ester; 4-CF3-StyrylBpin
EINECS	Contact for details

Quality Control

Our 4-Trifluoromethyl-trans-β-Styrylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (trans-isomer, HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.