Description

4,4,5,5-Tetramethyl-2-(4-Methylfuran-2-Yl)-1,3,2-Dioxaborolane CAS NO 1242517-59-4 is a high-purity, heterocyclic boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile and stable organoboron reagent, essential for facilitating key carbon-carbon bond-forming reactions. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed coupling with aryl/vinyl halides or triflates to form biaryl and other conjugated systems, crucial in pharmaceutical intermediate synthesis.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing furan-containing drug candidates with potential therapeutic applications.
• Agrochemical Development: Employed in creating novel fungicides, herbicides, and insecticides where the furan-boronate moiety imparts specific biological activity.
• Material Science & OLED Research: Acts as a precursor for organic electronic materials, including polymers and small molecules used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Probe Development: Utilized in synthesizing molecular probes and bioconjugation reagents for studying biological processes.
• Academic & Contract Research: Serves as a valuable tool for methodological development and complex molecule synthesis in university and CRO laboratory settings.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(4-Methylfuran-2-Yl)-1,3,2-Dioxaborolane
CAS No.	1242517-59-4
Molecular Formula	C₁₃H₂₁BO₃
Molecular Weight	236.12 g/mol
Synonyms	2-(4-Methyl-2-furyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methyl-2-furanylboronic acid pinacol ester; (4-Methylfuran-2-yl)boronic acid pinacol ester; 2-(4-Methylfuran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methyl-2-furylboronic Acid Pinacol Ester; Pinacol (4-Methyl-2-furyl)boronate; (4-Methyl-2-furyl)BPin
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(4-Methylfuran-2-Yl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR (¹H, ¹³C, ¹¹B), and GC analysis, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.