Description

1-Bromo-3-Fluoro-2-(Trifluoromethoxy)Benzene is a high-purity, multi-functional halogenated benzene derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering unique reactivity due to its specific pattern of bromo, fluoro, and trifluoromethoxy substituents. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, enabling rapid diversification of molecular scaffolds.
• Fluorine Chemistry Research: A valuable reagent for studying the effects of multiple fluorine atoms on aromatic systems in material science and medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	1-Bromo-3-Fluoro-2-(Trifluoromethoxy)Benzene
CAS No.	1242258-31-6
Molecular Formula	C7H3BrF4O
Molecular Weight	259.00 g/mol
Synonyms	2-Bromo-6-Fluoro-1-(Trifluoromethoxy)Benzene; 3-Fluoro-2-(trifluoromethoxy)bromobenzene; Benzene, 1-bromo-3-fluoro-2-(trifluoromethoxy)-; 1-Bromo-3-fluoro-2-(trifluoromethoxy)benzene; 2-(Trifluoromethoxy)-1-bromo-3-fluorobenzene; 1-Bromo-3-fluoro-2-trifluoromethoxybenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Fluoro-2-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reliable and consistent performance in sensitive synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.